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In recent years, the study of glacial geomorphology, a subdiscipline of earth science has gained significant attention due to its crucial role in understanding the impacts of climate change on our planet. Glacial geomorphology refers to studying the morphological features and processes that shape glaciers and their surrounding environments. One fascinating aspect of glacial geomorphology is the formation of glacial erratics, which are large rocks transported and deposited by glaciers in locations far from their sources. These erratics provide valuable insights into the history and dynamics of

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Conventional dosage forms and delivery systems present several challenges in treatment of diseases like poor bioavailability, high dose, frequent administration, systemic adverse effects, etc. Also, increasing prevalence of chronic diseases, high demand for non-invasive administration of drugs, need for high bioavailability and targeted delivery of drugs for lesser side effects have paved the way for innovation in drug delivery systems. Therefore, pharmaceutical companies are focused on designing novel drug delivery systems to overcome the limitations of using conventional dosage forms. For t

The breakthrough in the search for a coronavirus vaccine highlights the speed with which the pharmaceutical industry can mobilise scientific ingenuity in the service of humankind’s core goals. Yet, industry leaders know that such speed is the exception to the norm. Here, John Young, APAC director at automation parts supplier EU Automation, looks at four areas where greater automation could have a significant impact in helping speed the process of bringing a new drug to market in the years ahead.

The question which confuses people many a times is: are generics and biologics the same? And the answer is no, they are not the same. Let’s find out how.

Biologics are basically the products which are developed and produced from living organisms like human, plant or animal cells and, of course, microorganisms (bacteria, yeast, etc.). Having no definite structure, biologics are large and complex molecules which undergo sophisticated procedures while being developed and manufactured. Monoclonal antibodies, hormones, enzymes, insulin, etc. can be referred to as biologics.

This article explores the transformative shift toward patient-centric clinical trials, emphasizing active patient involvement in study design, recruitment strategies, and the integration of Patient-Reported Outcomes (PROs). By prioritizing transparency, communication, and digital health technologies, patient-centric trials enhance engagement, streamline recruitment, and improve data quality. The approach holds the potential to accelerate drug development, but challenges like regulatory hurdles and data privacy concerns must be addressed collaboratively for widespread implementation.

In drug discovery, AI is being used to predict the efficacy and safety of potential drug candidates, identify new therapeutic targets, and optimize clinical trial designs. By harnessing the power of machine learning algorithms, researchers can analyze vast amounts of biological data and identify patterns that are difficult to discern using traditional methods.

In drug manufacturing, AI is being used to optimize manufacturing processes, reduce costs, and ensure quality control. AI-powered predictive models can analyze data from multiple sources to identify potential issues and optimize prod

The concepts of Big Data and Big Data Analytics have been around for some time but it has only been since the late 1990’s, with the confluence of genomic and transcriptomic data, along with increased use of EHR’s and access to claims data, that Big Data has arrived at the shores of pharma and healthcare. This rapid and accelerating access has been frequently represented by Hokusai’s tidal wave (Figure 1) but this metaphor may be hiding the real challenges that we need to face to deliver more effective diagnoses, drugs and patient outcomes. A potential evolution of this model, to embrace the

Pharmaceutical companies are faced with the challenge of effectively managing and analyzing large volumes of data, which come in various formats, in order to extract meaningful and actionable insights. This is crucial for efficient drug development that balances cost and effectiveness. The use of cutting-edge technologies can help uncover the mechanisms of diseases, optimize clinical trials, and improve production efficiency and accuracy. By utilizing data analytics and automation, pharmaceutical companies can optimize their manufacturing processes and ensure timely and reliable delivery of d

Nanomaterials have been one of the most exciting scientific and technical innovations of the past few decades. Due to their very high surface to volume ratios, they exhibit properties that can differ dramatically from those for the same material in bulk. This, and their ability to be designed and synthesized with multiple surface functionalities, has seen them used for a myriad of bespoke applications in industry and medicine.

Their medical applications span delivery systems for drugs, proteins and DNA/RNA to diagnostics, targeted cancer treatments, to theranostics. They have been used ver

Precision drugs need to be defined and validated as having the molecular structure that would interact with a precisely defined disease target. Further, it must exhibit the right pharmacokinetics to facilitate the drugs’ efficacy. Ideally, onand off-target interactions should not cause disabling adverse events.

Precision drugs are yet to be discovered and developed. Drug discovery often starts with a “shot in the dark.” A huge number of compounds are often “filtered” in silico before being examined using high throughput screening to identify potentially relevant active compounds that are s

More than one billion people are impacted by chronic and acute lung diseases globally Infact, non-communicable diseases, such as chronic respiratory diseases are among the biggest reasons for fatality (WHO). Despite the growing health and wellness centricity across countries, respiratory conditions have not received the attention they need. If at all they do then it’s more for infectious conditions like Tuberculosis. But when wellness is looked at holistically, healthy lungs and lung health is paramount for overall health and wellbeing. According to WHO, respiratory illnesses lead to over 10p